About me

I am a teaching fellow at the Queen Mary University of London. My research interests include Cell Biology, Biochemistry, and Molecular Biology, and eager to learn/apply Machine Learning to exciting problems in my field.

My PhD research topic was to study the biochemical interactions between an important kinetochore protein, Astrin, and PP1; specifically investigating its role in kinetochore-microtubule interactions.

My PhD was supervised by Professor Viji Draviam, I was also part of DRAVIAM LAB

Previous Research and Experience

Teaching Fellow

I am working as a teaching fellow at the Queen Mary University of London. My duties includes deliver high-quality teaching, assessment, and supervision of undergraduate students, and to contribute to the life of the Department and the School by participating in groups / seminars, departmental meetings, and by undertaking administrative and advisory duties.

Post-doctoral Research Associate

I worked as a post-doctoral research associate to continue my investigation on Astrin-PP1 interactions. We used Biochemistry, Molecular Biology, and Cell Biology tools to understand Astrin’s biological role in cellular events including spindle movements, spindle orientation and the regulation of kinetochore-microtubule interactions.

Lecturer and Module Organizer

I worked at Coventry University as a university lecturer and module organizer in biology, my primary role was to design and deliver high-quality teaching and learning experiences for students. This involved variety of tasks, including; Developing course materials, Delivering lectures and tutorials, Assessing student performance, Providing support and guidance, and Conducting research labs.

PhD Grataue Researcher

My work investigates biochemical evidence for Astrin and PP1 interaction. My findings show that His-GST-PP1γ can pull-down endogenous Astrin isoforms. Conversely, bacterially expressed and purified C-terminal fragments of Astrin can pull-down endogenous PP1 gamma. To test the importance of Astrin-PP1 beyond chromosome-microtubule attachment, I trained myself with analyzing the process of spindle positioning in time-lapse movies of cells expressing Astrin-WT protein or Astrin 4A mutant compromised for Astrin-PP1 interaction. My image analysis studies show a role for Astrin-PP1 interaction in spindle orientation. Thus, my work set up the framework for studying Astrin-PP1 interaction biochemically and revealed the significance of this interaction in regulating mitotic spindle positioning during the cell division process.

Site Credits

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